Highlights
Light broaden the scope of alkene synthesis
October 15, 2024Chemists from the National University of Singapore (NUS) have developed a straightforward method to convert common chemicals like carboxylic acids,…
Read MoreModular assembly of ethylene, arenes and heteroarenes
July 17, 2024Chemists from the National University of Singapore (NUS) have developed a modular approach to create 1,2-arylheteroaryl ethanes, a class of…
Read MoreMultifunctional chiral alkylboron compounds by enantioselective nickel catalysis
March 20, 2024National University of Singapore (NUS) chemists have conceived a strategy using chiral nickel catalysts to facilitate the carboboration of alkenes,…
Read MoreEarth-abundant iron catalysis enables access to valuable dialkylated compounds
March 06, 2024National University of Singapore (NUS) chemists have solved a longstanding challenge in the synthesis of congested C(sp3)-rich molecules by developing…
Read MoreCatalyst for green production of fine chemicals and pharmaceuticals
October 11, 2023National University of Singapore (NUS) researchers have developed a new class of catalysts – known as heterogeneous geminal atom catalysts (GACs) – that promotes greener and more sustainable manufacturing processes for fine chemicals and pharmaceuticals.
Read MoreOn-demand preparation of organosilicon reagents
April 21, 2023National University of Singapore (NUS) scientists have demonstrated that stepwise customised functionalisation of multihydrosilanes to access fully substituted silicon compounds…
Read MoreChiral drug-like building blocks by nickel-catalysed enantioselective olefin cross-coupling
October 28, 2022NUS chemists have developed an effective method to access enantioenriched drug-like compounds through multicomponent olefin cross-coupling using chiral nickel-based catalysts….
Read MoreDirecting group-free alkene dicarbofunctionalization through catalyst control
December 24, 2021NUS chemists have developed a new “catalyst control” blueprint to overcome a longstanding challenge in the site-selective dicarbofunctionalization of unactivated…
Read MoreStereoselective alkene synthesis with non-precious nickel catalysis
August 10, 2021NUS chemists have developed a new way to access prized tri- and tetrasubstituted alkenes through a nickel-catalysed tandem process involving…
Read MoreManipulating chain-walking in olefins using earth-abundant iron-based catalysts
November 04, 2020NUS chemists have discovered a way of controlling the position of carbon-carbon double bonds (C=C) in olefin isomerisation using sustainable…
Read MoreDivergent synthesis of bicyclic medium-sized ring structures
October 26, 2020NUS chemists have discovered catalyst-controlled divergent reactions to synthesise three different classes of medium-sized bicyclic compounds from the same starting…
Read MoreSustainable iron catalysis enables controllable alkene borylation
June 09, 2020NUS chemists have unlocked a way to achieve site-selective borylation of alkenes using earth-abundant iron-based catalysts to facilitate synthesis of…
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