Highlights

Modular assembly of ethylene, arenes and heteroarenes

Modular assembly of ethylene, arenes and heteroarenes

July 17, 2024

Chemists from the National University of Singapore (NUS) have developed a modular approach to create 1,2-arylheteroaryl ethanes, a class of…

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Multifunctional chiral alkylboron compounds by enantioselective nickel catalysis

Multifunctional chiral alkylboron compounds by enantioselective nickel catalysis

March 20, 2024

National University of Singapore (NUS) chemists have conceived a strategy using chiral nickel catalysts to facilitate the carboboration of alkenes,…

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Earth-abundant iron catalysis enables access to valuable dialkylated compounds

Earth-abundant iron catalysis enables access to valuable dialkylated compounds

March 06, 2024

National University of Singapore (NUS) chemists have solved a longstanding challenge in the synthesis of congested C(sp3)-rich molecules by developing…

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Catalyst for green production of fine chemicals and pharmaceuticals

Catalyst for green production of fine chemicals and pharmaceuticals

October 11, 2023

National University of Singapore (NUS) researchers have developed a new class of catalysts – known as heterogeneous geminal atom catalysts (GACs) – that promotes greener and more sustainable manufacturing processes for fine chemicals and pharmaceuticals.

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On-demand preparation of organosilicon reagents

On-demand preparation of organosilicon reagents

April 21, 2023

National University of Singapore (NUS) scientists have demonstrated that stepwise customised functionalisation of multihydrosilanes to access fully substituted silicon compounds…

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Chiral drug-like building blocks by nickel-catalysed enantioselective olefin cross-coupling

Chiral drug-like building blocks by nickel-catalysed enantioselective olefin cross-coupling

October 28, 2022

NUS chemists have developed an effective method to access enantioenriched drug-like compounds through multicomponent olefin cross-coupling using chiral nickel-based catalysts….

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Directing group-free alkene dicarbofunctionalization through catalyst control

Directing group-free alkene dicarbofunctionalization through catalyst control

December 24, 2021

NUS chemists have developed a new “catalyst control” blueprint to overcome a longstanding challenge in the site-selective dicarbofunctionalization of unactivated…

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Stereoselective alkene synthesis with non-precious nickel catalysis

Stereoselective alkene synthesis with non-precious nickel catalysis

August 10, 2021

NUS chemists have developed a new way to access prized tri- and tetrasubstituted alkenes through a nickel-catalysed tandem process involving…

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Manipulating chain-walking in olefins using earth-abundant iron-based catalysts

Manipulating chain-walking in olefins using earth-abundant iron-based catalysts

November 04, 2020

NUS chemists have discovered a way of controlling the position of carbon-carbon double bonds (C=C) in olefin isomerisation using sustainable…

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Divergent synthesis of bicyclic medium-sized ring structures

Divergent synthesis of bicyclic medium-sized ring structures

October 26, 2020

NUS chemists have discovered catalyst-controlled divergent reactions to synthesise three different classes of medium-sized bicyclic compounds from the same starting…

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Sustainable iron catalysis enables controllable alkene borylation

Sustainable iron catalysis enables controllable alkene borylation

June 09, 2020

NUS chemists have unlocked a way to achieve site-selective borylation of alkenes using earth-abundant iron-based catalysts to facilitate synthesis of…

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Two (boron) is better than one

Two (boron) is better than one

March 28, 2019

NUS chemists have developed a cost effective method to synthesise geminal organodiboron compounds which are versatile chemical building blocks for…

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