Highlights
Unique multidomain enzymes from bacteria
October 28, 2024Pharmaceutical scientists from the National University of Singapore (NUS) have identified and characterised a unique multidomain enzyme capable of catalysing…
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Antimicrobial peptides with improved stability
August 14, 2023National University of Singapore (NUS) pharmaceutical scientists have successfully applied all-hydrocarbon-stapling modification to improve the enzymatic stability of their previously…
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Anti-microbial nanonets display multi-functionality by mitigating inflammatory responses during sepsis
May 22, 2023National University of Singapore (NUS) pharmaceutical scientists have developed multi-functional synthetic peptide nanonets for relieving inflammation caused by bacterial infection….
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Antimicrobial nanonets for trap-and-kill treatment of antibiotic-resistant bacteria
March 06, 2023National University of Singapore (NUS) pharmaceutical scientists have developed synthetic peptide nanonets for treating infections by bacteria strains resistant to…
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Nanovesicles from cells for biomedical applications
January 17, 2023NUS scientists have fabricated nano-sized vesicles from cells via a cell shearing approach that can be used for various biomedical…
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Virtual trials to streamline drug development
April 08, 2022NUS researchers have developed a model to predict the metabolism of an investigational product for optimising the drug formulation. In…
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Genome mining leads to a new type of peptide prenylation
May 19, 2021Researchers from NUS used a genome mining approach to identify a new cyclic peptide (tolypamide) derived from a cyanobacterium. The…
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Post-translational formation of strained cyclophanes in bacteria
October 15, 2020NUS researchers have identified post-translational modifying enzymes in bacteria that can create a new family of cyclic peptides for new…
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