Highlights

Novel method to synthesise valuable fluorinated drug compounds
February 21, 2025Researchers from the National University of Singapore (NUS) have pioneered a new catalytic transformation that converts epoxides …
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Light broaden the scope of alkene synthesis
October 15, 2024Chemists from the National University of Singapore (NUS) have developed a straightforward method to convert common chemicals like carboxylic acids,…
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Modular assembly of ethylene, arenes and heteroarenes
July 17, 2024Chemists from the National University of Singapore (NUS) have developed a modular approach to create 1,2-arylheteroaryl ethanes, a class of…
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Multifunctional chiral alkylboron compounds by enantioselective nickel catalysis
March 20, 2024National University of Singapore (NUS) chemists have conceived a strategy using chiral nickel catalysts to facilitate the carboboration of alkenes,…
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Earth-abundant iron catalysis enables access to valuable dialkylated compounds
March 06, 2024National University of Singapore (NUS) chemists have solved a longstanding challenge in the synthesis of congested C(sp3)-rich molecules by developing…
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Catalyst for green production of fine chemicals and pharmaceuticals
October 11, 2023National University of Singapore (NUS) researchers have developed a new class of catalysts – known as heterogeneous geminal atom catalysts (GACs) – that promotes greener and more sustainable manufacturing processes for fine chemicals and pharmaceuticals.
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On-demand preparation of organosilicon reagents
April 21, 2023National University of Singapore (NUS) scientists have demonstrated that stepwise customised functionalisation of multihydrosilanes to access fully substituted silicon compounds…
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Chiral drug-like building blocks by nickel-catalysed enantioselective olefin cross-coupling
October 28, 2022NUS chemists have developed an effective method to access enantioenriched drug-like compounds through multicomponent olefin cross-coupling using chiral nickel-based catalysts….
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Directing group-free alkene dicarbofunctionalization through catalyst control
December 24, 2021NUS chemists have developed a new “catalyst control” blueprint to overcome a longstanding challenge in the site-selective dicarbofunctionalization of unactivated…
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Stereoselective alkene synthesis with non-precious nickel catalysis
August 10, 2021NUS chemists have developed a new way to access prized tri- and tetrasubstituted alkenes through a nickel-catalysed tandem process involving…
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Manipulating chain-walking in olefins using earth-abundant iron-based catalysts
November 04, 2020NUS chemists have discovered a way of controlling the position of carbon-carbon double bonds (C=C) in olefin isomerisation using sustainable…
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Divergent synthesis of bicyclic medium-sized ring structures
October 26, 2020NUS chemists have discovered catalyst-controlled divergent reactions to synthesise three different classes of medium-sized bicyclic compounds from the same starting…
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