Pharmacy

The Department of Pharmacy advances and transforms the practice of pharmacy and pharmaceutical science through innovative teaching and breakthroughs in scientific discoveries relating to health, drugs and diseases. We remain top in Asia and 10th in the world in the Quacquarelli Symonds (QS) World University Rankings by Subject 2023: Pharmacy & Pharmacology.

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Future Talent

We recently reformed the undergraduate pharmacy curriculum, where we reimagine the Final Year Project as a new concept that brings together the innovative elements of ‘team-based medical / healthcare challenges’ and rigorous research methods. In this year-long Student-led Collaborative Innovative Pharmacy Inquiry (SCI-PhI) project, students worked on a subtopic in pairs or trios and integrated their findings from three subtopics to propose innovative solutions to a healthcare challenge. These solutions were presented to faculty members and external stakeholders on our inaugural SCI-PhI Day.

In Academic Year 2023 / 2024, we will commence a new interdisciplinary Common Curriculum in collaboration with the Alice Lee Centre for Nursing Studies, Faculty of Dentistry, Saw Swee Hock School of Public Health and Yong Loo Lin School of Medicine. The Common Curriculum seeks to cultivate awareness of social issues, professionalism and digital literacy in the context of healthcare. It will also equip students with collaborative skills to engage in population healthcare planning, delivery and evaluation.

Our part-time and full-time Master of Pharmacy (Clinical Pharmacy) programme will commence in Academic Year 2023 / 2024. This programme provides a stackable option to the Doctor of Pharmacy degree and will give learners enhanced flexibility and more diverse pathways to become advanced generalist and specialist pharmacy practitioners.

The inaugural full-time Master of Science (Pharmaceutical Science and Technology) cohort graduated this year.

10 budding pharmacists attended the inaugural Cardiometabolic, Renal & Diabetes Optimisation Unified Services (C-RIOUS) Workshop this year. The short course, delivered by a team of clinicians comprising cardiology specialist pharmacists, podiatrists, dieticians and more, focused on developing care plans for cardiometabolic diseases.

We support our students to help them fulfil their aspirations, in academics and beyond. 

The generosity of our benefactors also ensures they have access to the rich learning opportunities we offer.

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Future Solutions

Our researchers continue to make breakthroughs in health and disease management, with the discovery of novel compounds that have potential clinical and commercial use.

Nanomedicine to improve cancer treatments

Cancer is the leading cause of death in Singapore. Treatment outcomes are heavily influenced by cancer metabolism. Asst Prof TANG Wei’s team used nanotechology to disrupt cancer cell energy supply, thereby downregulating the synthesis of deoxyribonucleic acid (DNA) repair enzymes. This leads to improved radiosensitivity and reduced tumour acidity, which reprogrammes the tumour microenvironment to improve the efficacy of immunotherapy. This radiometabolic immunotherapy strategy shows potential in overcoming the significant challenge of cancer treatment resistance. This work received the National Medical Research Council Open Fund-Young Individual Research Grant (July 2022).

Biosynthetic enzymes to create peptide therapeutics

Asst Prof Brandon I MORINAKA’s team recently investigated a new enzyme family that catalyses macrocyclisation of peptides. The posttranslational cyclophane forming enzymes are found in a variety of bacteria. Their biosynthetic products offer potential antimicrobial properties. Macrocyclisation stabilises peptides so they can be taken orally and they also help in targeting specific diseases. This research expands the enzyme family and the chemical diversity that can be created using them. This study was published in the Journal of the American Chemical Society (June 2022) and ACS Chemical Biology (December 2022).

Topical pain relief for osteoarthritis

Osteoarthritis is a leading cause of chronic joint pain and morbidity worldwide. Dr Ayca ALTAY set up Team Pronio to help patients manage its debilitating effects without the need for costly surgery or painful steroid injections. The team has developed a novel topical gel that penetrates the skin in a noninvasive manner to alleviate pain.

Our students are also recognised for their research. Two of our students received the Outstanding Undergraduate Researcher Prize (OURP) in recognition of their work.

Our graduate students’ research also contribute to positive therapeutic outcomes that address diseases and health issues.

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Future Society

The inaugural Health T.A.G. (Test, Advise, Go) Fair, which we co-organised with the NUS Pharmaceutical Society, took place on 4 September 2022 at The Frontier Community Club. It drew around 220 participants and was graced by Minister for National Development Mr Desmond LEE, Chief Pharmacist Dr Camilla WONG and other stakeholders, including Boon Lay grassroots leaders and attendees from the Ministry of Health (MOH) Office for Healthcare Transformation. This was the first pharmacist-led health fair, planned and organised by our staff and students and supported by practicing pharmacists and nurses from Diabetes Singapore.

Our alumni contribute to society in many ways, some of them unconventional.

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Living in a quieter world

“I had amazing opportunities to enhance my academic experience and cultural exposure.”

Nicolette KOH, a Year 1 Pharmacy student, was diagnosed with profound hearing loss at the age of three. After finding that hearing aids did not help, she underwent three major surgeries during her childhood to get cochlear implants.

To Nicolette, life is a constant series of challenges. For instance, in school, she has to work harder to learn and process information as well as adapt to learning difficulties due to hearing loss.  

However, speech therapy, technological aids and the support of her professors and peers help her to fully embrace rich learning opportunities and manage social, educational, emotional and environmental challenges at the same time. Recently, she attended an exchange programme at the University of North Carolina at Chapel Hill, where she gained understanding on drug discovery and manufacturing as well as hospital laboratory testing. 

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Discovering purpose in suffering

“My cancer experience taught me to embrace change. Life is not always smooth-sailing and there may be circumstances that require me to realign my goals.”

Pharmacy alumnus (2023) Mr Matthew TAN’s studies were disrupted twice when he was diagnosed with lymphoma. Despite adversity, he rose above the storm and now uses his personal journey as a patient to empathise with his patients and help alleviate their grief and suffering.

Matthew credits his success to the support from his peers in the department and the Catholic Students’ Society, his professors who regularly checked in with him during his leaves of absence, and his mentors who provided listening ears and advice to steer his learning journey.

Matthew is currently a pre-registration pharmacist at the National University Hospital (NUH). He aspires to become an oncologist specialist pharmacist.

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Providing inclusive and accessible education

“The scholarship significantly reduced my family’s financial burden. It provided on-campus accommodation for my first two years of studies, which enabled me to forge friendships with students from diverse academic backgrounds.”

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Budding scientist

Year 4 student Eric LEOW, who reads Double Majors in Pharmaceutical Science and Computer Science, received the OURP for his project on the metabolism of cocaine. He found that the formation of benzoylecgonine from the breakdown of cocaine is mainly through nonenzymatic metabolism, challenging the current consensus that it is primarily driven by enzymatic metabolism. This study clarifies the interplay between enzymatic metabolism and nonenzymatic degradation of cocaine, which sets the stage for further studies on its disposition. 

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Budding scientist

Acute Myeloid Leukemia (AML) is an aggressive blood cancer associated with high relapse rates. Year 4 Pharmaceutical Science student LIM En Tong received the OURP for studying the expression of Cluster of Differentiation 47 (CD47) in drug-resistant AML cells and correlating its impact on immune evasion. CD47 is a protein on cellular surfaces that acts as a don’t eat me signal, preventing cells from being ingested by white blood cells. En Tong’s work sheds light on CD47 as a potential therapeutic target to mitigate relapse in AML patients.

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Budding scientist

Graduate student Angelica Faith SUAREZ characterises novel posttranslational enzymes that catalyse peptide cyclisation – an important chemical transformation used in creating peptide therapeutics. Her work was published in the Journal of the American Chemical Society (June 2022), showcasing the unique capabilities of these enzymes to create diverse peptide cyclophanes.

She was named to the Chemical Abstracts Service Future Leader Top 100 (2023) and also received the department’s Best Graduate Researcher (2023) award.

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Taking a shine to laboratory-grown diamonds

“My time in NUS taught me perseverance and to believe in myself. These are valuable life lessons in my journey as an entrepreneur.”

Pharmacy alumnus (2019) Mr Marcus WONG is behind the bespoke diamond jewellery brand which created the Miss Universe Singapore crown from 2021 to 2023. The Better Diamond was born out of Marcus’ interest in applying science and technology to replicate and grow diamonds in a controlled laboratory environment.

Laboratory-grown diamonds are a sustainable alternative to natural diamonds, as they are chemically, physically and optically identical – but without the negative ethical and environmental impacts associated with mined diamonds. The Better Diamond, one of the first of its kind in Singapore, specialises in handcrafting customised diamond jewellery from scratch, including diamonds in homeware and even car emblems! In the future, Marcus plans to expand The Better Diamond’s footprint overseas.

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New bent-toed gecko species in Timor-Leste

“We have barely scratched the surface of Timor-Leste’s biodiversity. New discoveries can have profound impacts on conservation and policy-making.”

In August 2022, we led an expedition to Timor-Leste in collaboration with Conservation International and the government of Timor-Leste. The Museum’s herpetologist, Dr CHAN Kin Onn, discovered a new species of bent-toed gecko which was named Cyrtodactylus santana, in reference to the Nino Konis Santana National Park, in which the gecko was discovered.