Research News from Faculty of Science

NUS physicists have designed and successively micro-fabricated a miniature ion beam source prototype, paving the way to improve ion beam brightness by up to a million times.
22 Mar 2017
Jeroen Anton VAN KAN (Group Leader, Physics)


NUS biologists have developed small peptides which are able to target cancer cells for anti-cancer therapeutics.
17 Mar 2017
GE Ruowen (Group Leader, Biological Sciences)


NUS physicists have found a new type of black hole that can exist in anti-de Sitter space, whose event horizon is infinite in extent yet has a finite area.
13 Mar 2017
Edward TEO (Group Leader, Physics)


NUS biologists are assembling a comprehensive checklist of bee species and their distributions to assess pollinator declines.
08 Mar 2017
John ASCHER (Group Leader, Biological Sciences)


NUS chemists discover that oxygen gas is vital for the alcohol dehydrogenation process at low temperatures.
02 Mar 2017
CHUAH Gaik Khuan (Group Leader, Chemistry)


NUS ecologists used a survey-based method to study the economic impacts of trans-boundary haze.
23 Feb 2017
Ryan CHISHOLM (Group Leader, Biological Sciences)


NUS chemists have developed a method to make two-dimensional (2D) polymers with high energy storage performance for batteries.
20 Feb 2017
LOH Kian Ping (Group Leader, Chemistry)


NUS mathematicians have developed effective methods for modelling real-life problems with monotone density ratio conditions.
16 Feb 2017
YU Tao (Group Leader, Statistics and Applied Probability)


NUS biological scientists discover hidden targets on dengue virus during transmission into human hosts.
10 Feb 2017
Ganesh ANAND (Group Leader, Biological Sciences)


NUS chemists have developed new iron-catalysed reactions for producing molecules used in pharmaceutical drug production.
06 Feb 2017
GE Shaozhong (Group Leader, Chemistry)


NUS statisticians gain insights which allow for better prediction of physical phenomena.
01 Feb 2017
Alexandre THIERY (Group Leader, Statistics and Applied Probability)


Green chemistry
Cooperativity in catalysis
NUS chemists have discovered an operationally simple process to synthesise Z-enediyne, a potent class of anticancer warhead.
25 Jan 2017
ZHAO Yu (Group Leader, Chemistry)


NUS statisticians have developed a method to estimate unknown parameters efficiently for modelling complex situations.
19 Jan 2017
David NOTT (Group Leader, Statistics and Applied Probability)


NUS biological scientists have unravelled principles underlying pulsatile cell dynamics, a key step towards understanding biological networks.
16 Jan 2017
Wu Min (Group Leader, Biological Sciences)


NUS statisticians have developed adaptive functional time series models that improve the forecast accuracy of complex data such as term structure of interest rates, limit order book liquidity and electricity price curves.
11 Jan 2017
CHEN Ying (Group Leader, Statistics and Applied Probability)


NUS pharmaceutical scientists have developed new antimicrobial peptides that are effective against multidrug-resistant tuberculosis.
06 Jan 2017
Rachel EE (Group Leader, Pharmacy)


NUS scientists have discovered how FTO (or fat mass and obesity-associated protein), a protein strongly associated with obesity and diabetes, opens new treatment options for these metabolic diseases.
03 Jan 2017
Esther WOON (Group Leader, Pharmacy)


NUS chemists have developed photo-catalysts with enhanced catalytic properties for wastewater treatment.
22 Dec 2016
Sam LI (Group Leader, Chemistry)


NUS physicists have discovered fluorescent concentric triangles in an atomically thin layer of semiconductor for potential optoelectronic applications.
19 Dec 2016
SOW Chorng Haur (Group Leader, Physics)


NUS clinician scientists have demonstrated the value of a screening tool to detect diabetes distress among the local patient population.
13 Dec 2016
Joyce LEE (Group Leader, Pharmacy)


NUS physicists have developed a new form of super-resolution fluorescence microscopy for biomedical applications by using highly focused mega-electron volt (MeV) ion beams.
07 Dec 2016
Andrew BETTIOL (Group Leader, Physics)


NUS chemists have developed a synthesis approach to link semiconductor nanoparticles in a site-specific, stoichiometrically controlled manner analogous to molecular synthesis.
01 Dec 2016
CHAN Yin Thai (Group Leader, Chemistry)


NUS marine researchers are boosting local marine research and sustainability efforts to cope with emerging challenges brought about by climate change and urbanisation.
28 Nov 2016
Peter TODD and HUANG Danwei (Group Leaders, Biological Sciences)


NUS scientists in collaboration with Cambridge Display Technology Ltd (CDT) have developed solution-processed conducting polymer materials with ultrawide range of work functions for flexible electronics.
24 Nov 2016
Peter HO and CHUA Lay-Lay (Group Leaders, Physics and Chemistry)


Materials science
Tortuous path to nanocrystals
NUS researchers observed the crystallisation of gold particles in real-time in an aqueous solution in clear violation of classical nucleation theory.
21 Nov 2016
Utkur MIRSAIDOV and Duane LOH (Group Leaders, Physics and Biological Sciences)


NUS mathematicians have developed an unbiased and consistent estimator for counting motif (pattern) of gene regulatory relationships.
17 Nov 2016
ZHANG Louxin (Group Leader, Mathematics)


NUS mathematicians have developed an efficient and stable numerical method to solve fluid structure interaction problems involving large convections of fluid and near-contact of structures.
14 Nov 2016
LIU Jie (Group Leader, Mathematics)


NUS pharmaceutical scientists have developed techniques to modify lactose carrier particles in dry powder inhalers for efficient drug delivery to the lungs.
10 Nov 2016
Paul HENG (Group Leader, Pharmacy)


NUS biologist is part of the team that have discovered an important step in the development of ALS (amyotrophic lateral sclerosis), a neurodegenerative disease that is fatal.
07 Nov 2016
Kunchithapadam SWAMINATHAN (Group Leader, Biological Sciences)


NUS biologists have discovered a mechanism explaining why motor neurons are more vulnerable and degenerate first in a common neurodegenerative disease.
03 Nov 2016
Christoph WINKLER (Group Leader, Biological Sciences)


NUS scientists have published a report to revise the 30-year old polaron band model for doped organic semiconductors.
31 Oct 2016
Peter HO and CHUA Lay-Lay (Group Leaders, Physics and Chemistry)


NUS scientists have developed the first scaleable robust, open-sourced reconstruction algorithm targeted specifically for lens-less imaging with x-ray lasers.
27 Oct 2016
Duane LOH (Group Leader, Biological Sciences and Physics)


NUS mathematicians have provided a theoretical justification of trend-following trading strategies.
24 Oct 2016
DAI Min (Group Leader, Mathematics)


NUS scientists have developed on-chip molecular electronic plasmon sources without using optical elements for ultra-high speed electronics.
19 Oct 2016
Christian NIJHUIS (Group Leader, Chemistry)


NUS marine ecologists develop structurally complex tiles with relevant microhabitats and a large-scale deployment strategy for enhancing intertidal biodiversity on seawalls in Singapore.
14 Oct 2016
Peter TODD (Group Leader, Biological Sciences)


NUS biologists used a safe insect virus as gene therapy vectors to treat bladder cancer in mouse tumour models.
13 Oct 2016
WANG Shu (Group Leader, Biological Sciences)


NUS biologists have discovered that campotothecin (CPT), a highly selective DNA topoisomerase 1 (TOP1) inhibitor, targets stem cells in the root of the non-CPT-producing weed Arabidopsis thaliana.
10 Oct 2016
XU Jian (Group Leader, Biological Sciences)


NUS physicists have developed a high performance photodetector built on a hybrid bilayer of tungsten diselenide (WSe2) and perovskite.
06 Oct 2016
SOW Chorng Haur (Group Leader, Physics)


NUS food scientists discovered that human smell sensitivity changes with age, depending on the type of smells.
03 Oct 2016
HUANG Dejian (Group Leader, Chemistry)


NUS researchers establish association between dam construction and the increase in the proportion of non-native species in freshwater fish communities.
29 Sep 2016
Darren YEO (Group Leader, Biological Sciences)


NUS researchers have discovered that a protein, present in cells - talin - is able to sense and buffer cells against external forces.
26 Sep 2016
YAN Jie (Group Leader, Physics)


NUS food scientists have developed an edible coating which can preserve the quality of chilled fish fillets.
22 Sep 2016
YANG Hongshun (Group Leader, Chemistry)


NUS pharmacists discover that the quality of life of pre-dialysis patients may be affected more by a pill burden than complications associated with chronic kidney disease (CKD).
20 Sep 2016
Priscilla HOW (Group Leader, Pharmacy)


NUS scientists have discovered the mechanism of aggregation enhanced two-photon photoluminescence (2PPL) of metal nanoparticles by studying 2PPL properties of Au nanorod-nanosphere (NR-NS) heterodimers on the single particle level.
15 Sep 2016
XU Qing Hua (Group Leader, Chemistry)


NUS pharmacists have discovered signatures of diabetic retinopathy in blood samples which can identify those at a higher risk.
13 Sep 2016
Eric CHAN (Group Leader, Pharmacy)


NUS chemists have developed a new method of using phosphine catalysts to produce organic compounds with high stereoselectivity.
08 Sep 2016
LU Yixin (Group Leader, Chemistry)


Statistical methodology
Taking the high road
NUS statisticians have developed a “slope-assisted Hamiltonian Monte Carlo” sampling method to draw samples automatically from complex posterior distributions.
05 Sep 2016
Sanjay CHAUDHURI (Group Leader, Statistics and Applied Probability)


Electrochemistry
Greening our world
NUS chemists have developed a type of copper-based catalyst, which could efficiently reduce carbon dioxide, a greenhouse gas, into n-propanol.
01 Sep 2016
Jason YEO (Group Leader, Chemistry)


NUS mathematicians have formulated an equation for designing efficient memory allocation techniques for computer systems.
29 Sep 2016
TAY Yong Chiang (Group Leader, Mathematics)


NUS biologists have developed an effective method for protein extraction from green algae to detect environmental pollutants.
25 Aug 2016
LIN Qingsong (Group Leader, Biological Sciences)


Advanced materials
A new class of materials
NUS physicists and collaborators have developed ultra-thin films of a new class of materials: Weyl semi-metals.
22 Aug 2016
Adam SHAFFIQUE (Group Leader, Physics)


NUS scientists have found that most tropical butterflies tend to feed on a variety of flowers but some species are very selective in their diet.
19 Aug 2016
Edward WEBB (Group Leader, Biological Sciences)


NUS food scientists proved the potential of blue light-emitting diodes (LEDs) in killing deadly bacteria in orange juice.
15 Aug 2016
YUK Hyun-Gyun (Group Leader, Chemistry)


NUS scientists used flies to document rapid changes in the evolution of genome size in animals.
11 Aug 2016
Rudolf MEIER (Group Leader, Biological Sciences)


NUS scientists have developed multi-component nanocomposites which function as efficient visible-light photocatalysts with excellent magnetic recoverability.
08 Aug 2016
CHEN Wei (Group Leader, Chemistry and Physics)


Scientists in NUS conducted field experiments using paper models of butterflies to show how particular features of their wing patterns affected predation risk in the wild.
04 Aug 2016
Antónia MONTEIRO (Group Leader, Biological Sciences)


Advanced materials
A see-through metal
NUS scientists discover a way to enhance light transmission through an opaque metal surface by adding an atomically thin layer of semiconductor.
01 Aug 2016
Goki EDA (Group Leader, Chemistry and Physics)


NUS statisticians have developed a model which accounts for hidden factors and their effects for improved accuracy from economic data.
27 Jul 2016
LI Jialiang (Group Leader, Statistics and Applied Probability)


NUS scientists have synthesised the cDNA clone of the Brazilian variant of the hibiscus plant virus.
25 Jul 2016
WONG Sek Man (Group Leader, Biological Sciences)


NUS researchers develop a new theory which captures the dramatic fluctuations in species population abundances often observed in nature.
21 Jul 2016
Ryan CHISHOLM (Group Leader, Biological sciences)


NUS food scientists come up with the world’s first coffee fermented the old-fashioned way, with a food grade fungus Rhizopus oligosporus.
18 Jul 2016
LIU Shao Quan (Group Leader, Chemistry)


NUS biological scientists have identified the genes responsible for defending stem cells against viral infections.
14 Jul 2016
Jonathan LOH (Group Leader, Biological Sciences)


NUS chemists have developed a model for designing cell-permeable fluorescent probes with little background interference for bioimaging of living cells.
11 Jul 2016
CHANG Young-Tae (Group Leader, Chemistry)


NUS biophysicists have invented an artificial enzymatic nanowalker with record fuel efficiency by mimicking biological counterparts.
07 Jul 2016
WANG Zhisong (Group Leader, Physics)


NUS scientists have developed an optical method for measuring the instantaneous Brownian velocity of colloidal suspensions using upconversion nanothermometry.
05 Jul 2016
LIU Xiaogang (Group Leader, Chemistry)


NUS scientists have developed research which establishes the correctness of numerical methods used for important statistical applications.
30 Jun 2016
Ajay JASRA (Group Leader, Statistics and Applied Probability)


Organic chemistry
Resisting the urge to burn!
NUS researchers have developed new halodefluorination reaction with potential for new flame retardant materials.
27 Jun 2016
Rowan YOUNG (Group Leader, Chemistry)


NUS scientists have discovered new molecules which have a dual action to combat resistant malaria.
23 Jun 2016
Brian DYMOCK (Group Leader, Pharmacy)


Scientists in NUS discovered novel defect states at grain boundaries (GBs) in a two-dimensional (2D) semiconductor.
20 Jun 2016
Andrew WEE (Group Leader, Physics)


NUS scientists have identified the protein MOAP-1 as a potential treatment target for acute liver failure triggered by activation of a cell suicide program.
17 Jun 2016
Victor YU (Group Leader, Pharmacy)


Scientists in NUS discovered that Google Trends search patterns show that interest on key conservation topics is not declining over time and that search peaks are driven by online news.
13 Jun 2016
Roman CARRASCO (Group Leader, Biological Sciences)


Food scientists in NUS have identified a potent and highly selective inhibitor from traditional Chinese medicine, called dragon’s blood, to control high blood glucose.
09 Jun 2016
HUANG Dejian (Group Leader, Chemistry)


NUS scientists discovered a molecular mechanism which allows cellular processes to control the physiology and proteinopathy of TDP-43 whose aggregation is characteristic of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and many other ageing-related human diseases.
07 Jun 2016
SONG Jianxing (Group Leader, Biological Sciences)


NUS physicists have observed special photoresponse behaviour from a new two-dimensional (2D) semiconductor.
02 Jun 2016
SOW Chorng Haur (Group Leader, Physics)


NUS scientists have discovered Floquet topological semimetal phases in a simple dynamical model.
30 May 2016
GONG Jiangbin (Group Leader, Physics)


NUS physicists discovered a new way of transferring magnetic information across an insulator, paving the way for the development of devices that operate in the teraherz frequency range.
25 May 2016
ARIANDO (Group Leader, Physics)


NUS scientists have discovered a unique demonstration of how biomimetic interfaces can be used to probe and understand the influence of the microenvironment on the cellular process.
23 May 2016
Virgile VIASNOFF (Group Leader, Biological Sciences)


NUS scientists have developed a simple sampling method for soft fruit flesh using a conventional syringe needle for mapping the three-dimensional (3D) distribution of vitamin C.
19 May 2016
LEE Hian Kee (Group Leader, Chemistry)


Scientists in NUS discovered new small synthetic molecules with the aim of each molecule inhibiting two enzymes simultaneously, thus giving rise to potential anticancer properties.
16 May 2016
CHUI Wai Keung (Group Leader, Pharmacy)


NUS food scientists explore and expand the potential use of soybean residue (okara), a food processing waste, by yeast fermentation.
13 May 2016
LIU Shao-Quan (Group Leader, Chemistry)


NUS physicists have shown that giant photoluminescence (PL) enhancement is demonstrated by suspending the two-dimensional (2D) semiconductor WSe2 on sub-20 nanometre (nm) wide trenches in gold nanoarray substrates.
09 May 2016
Andrew WEE (Group Leader, Physics)


Scientists in NUS developed a new strategy to prepare acene dimers which have extremely high stability in ambient light and air conditions.
07 May 2016
CHI Chunyan (Group Leader, Chemistry)


Mechanobiology & Molecular cells
Mechanical barrier to cancer cell proliferation
Researchers in NUS discovered the differential effect of extracellular matrix (ECM) topographical cues on healthy and cancer cell proliferation.
05 May 2016
LOW Boon Chuan (Group Leader, Biological sciences)


NUS scientists have identified bacterial osmoporin OmpC as a functional component of the system that maintains outer membrane lipid asymmetry.
03 May 2016
CHNG Shu Sin (Group Leader, Chemistry)


NUS scientist wins the Young Researcher Award for ground-breaking work in molecular electronics.
29 Apr 2016
Christian NIJHUIS (Group Leader, Chemistry)


Bioimaging sciences
Diffraction before destruction
Scientists in NUS have demonstrated how x-ray lasers could help us image biological macromolecules in water.
26 Apr 2016
Duane LOH (Group Leader, Biological Sciences)


Scientists in NUS have uncovered a novel function of Nucleolar spindle-associated protein (NuSAP) in chromosome segregation.
22 Apr 2016
LIOU Yih-Cherng (Group Leader, Biological sciences)


NUS scientists have discovered for the first time that dronedarone inhibits human cardiac cytochrome P450 2J2 (CYP2J2).
18 Apr 2016
Eric CHAN (Group Leader, Pharmacy)


NUS biophysicists have developed a new generation of nanomotors, which potentially serve as ‘engines’ to power future nanotechnology at large.
14 Apr 2016
WANG Zhisong (Group Leader, Physics)


Mathematicians in NUS have developed a new theory and technique for database query optimisation.
11 Apr 2016
TAY Yong Chiang (Group Leader, Mathematics)


An in situ Transmission Electron Microscopy (TEM) study reveals that water molecules bound to nanoparticle surfaces serve as a barrier that stall their pairwise attachment.
07 Apr 2016
Utkur MIRSAIDOV (Group Leader, Biological Sciences)


Structural biology
New hope for HBV carriers
NUS scientists have discovered the mechanisms of mAb mediated HBsAg clean-up, a critical step towards development of therapeutic mAbs for Hepatitis B virus (HBV) carrier treatment.
04 Apr 2016
Adam YUAN (Group Leader, Biological Sciences)


NUS biologists discovered the mechanistic understanding of silk formation, the spinning process, and property-structure relationship as the key to mass-produce man-made spider silk.
29 Mar 2016
YANG Daiwen (Group Leader, Biological Sciences)


NUS food scientists have shown that fortifying bread with anthocyanin-rich extract slows down its digestion rate and adds health benefits.
28 Mar 2016
ZHOU Weibiao (Group Leader, Chemistry)


NUS scientists reported that international trade causes large net economic losses in tropical countries through the destruction of ecosystem services.
24 Mar 2016
Roman CARRASCO (Group Leader, Biological Sciences)


NUS food scientists develop the eucheuma-based packaged beverages with no added sugar and preservatives with a local company YGC Group.
21 Mar 2016
YANG Hongshun (Group Leader, Chemistry)


NUS scientists discover new organoruthenium anticancer complexes able to overcome multidrug resistance (MDR) by inducing alternative modes of cell death.
17 Mar 2016
ANG Wee Han (Group Leader, Chemistry)


Biodiversity
A new frog species
Researchers in NUS engage with citizens in India to describe the new species of frog as Microhyla laterite.
14 Mar 2016
Seshadri K S (Group Leader, Biological Sciences)


Scientists in NUS discovered visible surface plasmon modes in Bi2Te3 topological insulator nanoplates and obtained real space imaging of the plasmon modes for the first time.
11 Mar 2016
LOH Kian Ping (Group Leader, Chemistry)


NUS scientists invent new method and are planning to apply it to estimate undetected extinction in a wide range of animals and plants to assess impacts of deforestation and/or urbanisation on nature.
08 Mar 2016
Ryan CHISHOLM (Group Leader, Biological Sciences)


Researchers from NUS and the A*STAR designed a friendly inhalation treatment for a rare but serious condition.
04 Mar 2016
CHAN Sui Yung (Group Leader, Pharmacy)


NUS scientists have established the mechanisms for spin motion in molybdenum disulfide, an emerging two-dimensional (2D) material.
29 Feb 2016
Goki EDA (Group Leader, Physics)


NUS scientists are studying how to stop blood from clotting while not causing uncontrollable bleeding at similar doses.
25 Feb 2016
Kini R MANJUNATHA (Group Leader, Biological Sciences)


Scientists in NUS have developed a very low threshold, multi-photon pumped laser based on a solution of colloidal semiconductor nanoplatelets in a thin quartz cuvette.
23 Feb 2016
CHAN Yin Thai (Group Leader, Chemistry)


NUS scientists discovered that the dynamics of an “insoluble” protein and its interaction with membranes hold clues for the mechanism and progression of ALS.
15 Feb 2016
SONG Jianxing (Group Leader, Biological Sciences)


NUS researchers developed photomasks consisting of microlenses to make microneedles.
12 Feb 2016
KANG Li Feng (Group Leader, Pharmacy)


Computational mathematics
Wetting transition on patterned surfaces
NUS mathematicians investigate the liquid-vapour transition on patterned surfaces in shear flow using the minimum action method developed based on the large deviation theory.
10 Feb 2016
REN Weiqing (Group Leader, Mathematics)


NUS scientists discover that a plant-type Pin1, Pin1At, a peptidyl-prolyl isomerase, can regulate root growth in response to gravity by mediating a hormone pathway in plants.
05 Feb 2016
LIOU Yih-Cherng (Group Leader, Biological Sciences)


NUS scientists have discovered new molecules which release small amounts of H2S gas resulting in potent anti-cancer effects.
02 Feb 2016
Brian DYMOCK (Group Leader, Pharmacy)


NUS scientists have investigated how different transcription factors interact in embryonic and neuronal stem cells.
29 Jan 2016
Thorsten WOHLAND (Group Leader, Biological Sciences)


Organic chemistry
A new synthetic method
NUS chemists reported a new synthetic method of introducing an alkynyl group at β-position of cyclic carbonyl compounds with high enantioselectivity.
21 Jan 2016
Tamio HAYASH (Group Leader, Chemistry)


NUS pharmaceutical scientists showed remarkable improvement in oral absorption of HIV drugs.
18 Jan 2016
Gigi CHIU (Group Leader, Pharmacy)


NUS scientists studied the regulatory system, recruiting machinery and translocation apparatus to deliver-virulence proteins into host cells to cause infection.
13 Jan 2016
Jayaraman SIVARAMAN (Group Leader, Biological Sciences)


NUS scientist wins the 2015 L’Oréal FWIS National Fellowship in conservation of giant clams.
09 Jan 2016
NEO Mei Lin (Group Leader, Biological Sciences)


NUS professors measured phonon modes during hexagonal boron nitride growth using a surface sensitive technique.
05 Jan 2016
LOH Kian Ping (Group Leader, Chemistry)


Research News from Faculty of Science

NUS physicists have designed and successively micro-fabricated a miniature ion beam source prototype, paving the way to improve ion beam brightness by up to a million times.
22 Mar 2017
Jeroen Anton VAN KAN (Group Leader, Physics)


NUS biologists have developed small peptides which are able to target cancer cells for anti-cancer therapeutics.
17 Mar 2017
GE Ruowen (Group Leader, Biological Sciences)


NUS physicists have found a new type of black hole that can exist in anti-de Sitter space, whose event horizon is infinite in extent yet has a finite area.
13 Mar 2017
Edward TEO (Group Leader, Physics)


NUS biologists are assembling a comprehensive checklist of bee species and their distributions to assess pollinator declines.
08 Mar 2017
John ASCHER (Group Leader, Biological Sciences)


NUS chemists discover that oxygen gas is vital for the alcohol dehydrogenation process at low temperatures.
02 Mar 2017
CHUAH Gaik Khuan (Group Leader, Chemistry)


NUS ecologists used a survey-based method to study the economic impacts of trans-boundary haze.
23 Feb 2017
Ryan CHISHOLM (Group Leader, Biological Sciences)


NUS chemists have developed a method to make two-dimensional (2D) polymers with high energy storage performance for batteries.
20 Feb 2017
LOH Kian Ping (Group Leader, Chemistry)


NUS mathematicians have developed effective methods for modelling real-life problems with monotone density ratio conditions.
16 Feb 2017
YU Tao (Group Leader, Statistics and Applied Probability)


NUS biological scientists discover hidden targets on dengue virus during transmission into human hosts.
10 Feb 2017
Ganesh ANAND (Group Leader, Biological Sciences)


NUS chemists have developed new iron-catalysed reactions for producing molecules used in pharmaceutical drug production.
06 Feb 2017
GE Shaozhong (Group Leader, Chemistry)


NUS statisticians gain insights which allow for better prediction of physical phenomena.
01 Feb 2017
Alexandre THIERY (Group Leader, Statistics and Applied Probability)


Green chemistry
Cooperativity in catalysis
NUS chemists have discovered an operationally simple process to synthesise Z-enediyne, a potent class of anticancer warhead.
25 Jan 2017
ZHAO Yu (Group Leader, Chemistry)


NUS statisticians have developed a method to estimate unknown parameters efficiently for modelling complex situations.
19 Jan 2017
David NOTT (Group Leader, Statistics and Applied Probability)


NUS biological scientists have unravelled principles underlying pulsatile cell dynamics, a key step towards understanding biological networks.
16 Jan 2017
Wu Min (Group Leader, Biological Sciences)


NUS statisticians have developed adaptive functional time series models that improve the forecast accuracy of complex data such as term structure of interest rates, limit order book liquidity and electricity price curves.
11 Jan 2017
CHEN Ying (Group Leader, Statistics and Applied Probability)


NUS pharmaceutical scientists have developed new antimicrobial peptides that are effective against multidrug-resistant tuberculosis.
06 Jan 2017
Rachel EE (Group Leader, Pharmacy)


NUS scientists have discovered how FTO (or fat mass and obesity-associated protein), a protein strongly associated with obesity and diabetes, opens new treatment options for these metabolic diseases.
03 Jan 2017
Esther WOON (Group Leader, Pharmacy)


NUS chemists have developed photo-catalysts with enhanced catalytic properties for wastewater treatment.
22 Dec 2016
Sam LI (Group Leader, Chemistry)


NUS physicists have discovered fluorescent concentric triangles in an atomically thin layer of semiconductor for potential optoelectronic applications.
19 Dec 2016
SOW Chorng Haur (Group Leader, Physics)


NUS clinician scientists have demonstrated the value of a screening tool to detect diabetes distress among the local patient population.
13 Dec 2016
Joyce LEE (Group Leader, Pharmacy)


NUS physicists have developed a new form of super-resolution fluorescence microscopy for biomedical applications by using highly focused mega-electron volt (MeV) ion beams.
07 Dec 2016
Andrew BETTIOL (Group Leader, Physics)


NUS chemists have developed a synthesis approach to link semiconductor nanoparticles in a site-specific, stoichiometrically controlled manner analogous to molecular synthesis.
01 Dec 2016
CHAN Yin Thai (Group Leader, Chemistry)


NUS marine researchers are boosting local marine research and sustainability efforts to cope with emerging challenges brought about by climate change and urbanisation.
28 Nov 2016
Peter TODD and HUANG Danwei (Group Leaders, Biological Sciences)


NUS scientists in collaboration with Cambridge Display Technology Ltd (CDT) have developed solution-processed conducting polymer materials with ultrawide range of work functions for flexible electronics.
24 Nov 2016
Peter HO and CHUA Lay-Lay (Group Leaders, Physics and Chemistry)


Materials science
Tortuous path to nanocrystals
NUS researchers observed the crystallisation of gold particles in real-time in an aqueous solution in clear violation of classical nucleation theory.
21 Nov 2016
Utkur MIRSAIDOV and Duane LOH (Group Leaders, Physics and Biological Sciences)


NUS mathematicians have developed an unbiased and consistent estimator for counting motif (pattern) of gene regulatory relationships.
17 Nov 2016
ZHANG Louxin (Group Leader, Mathematics)


NUS mathematicians have developed an efficient and stable numerical method to solve fluid structure interaction problems involving large convections of fluid and near-contact of structures.
14 Nov 2016
LIU Jie (Group Leader, Mathematics)


NUS pharmaceutical scientists have developed techniques to modify lactose carrier particles in dry powder inhalers for efficient drug delivery to the lungs.
10 Nov 2016
Paul HENG (Group Leader, Pharmacy)


NUS biologist is part of the team that have discovered an important step in the development of ALS (amyotrophic lateral sclerosis), a neurodegenerative disease that is fatal.
07 Nov 2016
Kunchithapadam SWAMINATHAN (Group Leader, Biological Sciences)


NUS biologists have discovered a mechanism explaining why motor neurons are more vulnerable and degenerate first in a common neurodegenerative disease.
03 Nov 2016
Christoph WINKLER (Group Leader, Biological Sciences)


NUS scientists have published a report to revise the 30-year old polaron band model for doped organic semiconductors.
31 Oct 2016
Peter HO and CHUA Lay-Lay (Group Leaders, Physics and Chemistry)


NUS scientists have developed the first scaleable robust, open-sourced reconstruction algorithm targeted specifically for lens-less imaging with x-ray lasers.
27 Oct 2016
Duane LOH (Group Leader, Biological Sciences and Physics)


NUS mathematicians have provided a theoretical justification of trend-following trading strategies.
24 Oct 2016
DAI Min (Group Leader, Mathematics)


NUS scientists have developed on-chip molecular electronic plasmon sources without using optical elements for ultra-high speed electronics.
19 Oct 2016
Christian NIJHUIS (Group Leader, Chemistry)


NUS marine ecologists develop structurally complex tiles with relevant microhabitats and a large-scale deployment strategy for enhancing intertidal biodiversity on seawalls in Singapore.
14 Oct 2016
Peter TODD (Group Leader, Biological Sciences)


NUS biologists used a safe insect virus as gene therapy vectors to treat bladder cancer in mouse tumour models.
13 Oct 2016
WANG Shu (Group Leader, Biological Sciences)


NUS biologists have discovered that campotothecin (CPT), a highly selective DNA topoisomerase 1 (TOP1) inhibitor, targets stem cells in the root of the non-CPT-producing weed Arabidopsis thaliana.
10 Oct 2016
XU Jian (Group Leader, Biological Sciences)


NUS physicists have developed a high performance photodetector built on a hybrid bilayer of tungsten diselenide (WSe2) and perovskite.
06 Oct 2016
SOW Chorng Haur (Group Leader, Physics)


NUS food scientists discovered that human smell sensitivity changes with age, depending on the type of smells.
03 Oct 2016
HUANG Dejian (Group Leader, Chemistry)


NUS researchers establish association between dam construction and the increase in the proportion of non-native species in freshwater fish communities.
29 Sep 2016
Darren YEO (Group Leader, Biological Sciences)


NUS researchers have discovered that a protein, present in cells - talin - is able to sense and buffer cells against external forces.
26 Sep 2016
YAN Jie (Group Leader, Physics)


NUS food scientists have developed an edible coating which can preserve the quality of chilled fish fillets.
22 Sep 2016
YANG Hongshun (Group Leader, Chemistry)


NUS pharmacists discover that the quality of life of pre-dialysis patients may be affected more by a pill burden than complications associated with chronic kidney disease (CKD).
20 Sep 2016
Priscilla HOW (Group Leader, Pharmacy)


NUS scientists have discovered the mechanism of aggregation enhanced two-photon photoluminescence (2PPL) of metal nanoparticles by studying 2PPL properties of Au nanorod-nanosphere (NR-NS) heterodimers on the single particle level.
15 Sep 2016
XU Qing Hua (Group Leader, Chemistry)


NUS pharmacists have discovered signatures of diabetic retinopathy in blood samples which can identify those at a higher risk.
13 Sep 2016
Eric CHAN (Group Leader, Pharmacy)


NUS chemists have developed a new method of using phosphine catalysts to produce organic compounds with high stereoselectivity.
08 Sep 2016
LU Yixin (Group Leader, Chemistry)


Statistical methodology
Taking the high road
NUS statisticians have developed a “slope-assisted Hamiltonian Monte Carlo” sampling method to draw samples automatically from complex posterior distributions.
05 Sep 2016
Sanjay CHAUDHURI (Group Leader, Statistics and Applied Probability)


Electrochemistry
Greening our world
NUS chemists have developed a type of copper-based catalyst, which could efficiently reduce carbon dioxide, a greenhouse gas, into n-propanol.
01 Sep 2016
Jason YEO (Group Leader, Chemistry)


NUS mathematicians have formulated an equation for designing efficient memory allocation techniques for computer systems.
29 Sep 2016
TAY Yong Chiang (Group Leader, Mathematics)


NUS biologists have developed an effective method for protein extraction from green algae to detect environmental pollutants.
25 Aug 2016
LIN Qingsong (Group Leader, Biological Sciences)


Advanced materials
A new class of materials
NUS physicists and collaborators have developed ultra-thin films of a new class of materials: Weyl semi-metals.
22 Aug 2016
Adam SHAFFIQUE (Group Leader, Physics)


NUS scientists have found that most tropical butterflies tend to feed on a variety of flowers but some species are very selective in their diet.
19 Aug 2016
Edward WEBB (Group Leader, Biological Sciences)


NUS food scientists proved the potential of blue light-emitting diodes (LEDs) in killing deadly bacteria in orange juice.
15 Aug 2016
YUK Hyun-Gyun (Group Leader, Chemistry)


NUS scientists used flies to document rapid changes in the evolution of genome size in animals.
11 Aug 2016
Rudolf MEIER (Group Leader, Biological Sciences)


NUS scientists have developed multi-component nanocomposites which function as efficient visible-light photocatalysts with excellent magnetic recoverability.
08 Aug 2016
CHEN Wei (Group Leader, Chemistry and Physics)


Scientists in NUS conducted field experiments using paper models of butterflies to show how particular features of their wing patterns affected predation risk in the wild.
04 Aug 2016
Antónia MONTEIRO (Group Leader, Biological Sciences)


Advanced materials
A see-through metal
NUS scientists discover a way to enhance light transmission through an opaque metal surface by adding an atomically thin layer of semiconductor.
01 Aug 2016
Goki EDA (Group Leader, Chemistry and Physics)


NUS statisticians have developed a model which accounts for hidden factors and their effects for improved accuracy from economic data.
27 Jul 2016
LI Jialiang (Group Leader, Statistics and Applied Probability)


NUS scientists have synthesised the cDNA clone of the Brazilian variant of the hibiscus plant virus.
25 Jul 2016
WONG Sek Man (Group Leader, Biological Sciences)


NUS researchers develop a new theory which captures the dramatic fluctuations in species population abundances often observed in nature.
21 Jul 2016
Ryan CHISHOLM (Group Leader, Biological sciences)


NUS food scientists come up with the world’s first coffee fermented the old-fashioned way, with a food grade fungus Rhizopus oligosporus.
18 Jul 2016
LIU Shao Quan (Group Leader, Chemistry)


NUS biological scientists have identified the genes responsible for defending stem cells against viral infections.
14 Jul 2016
Jonathan LOH (Group Leader, Biological Sciences)


NUS chemists have developed a model for designing cell-permeable fluorescent probes with little background interference for bioimaging of living cells.
11 Jul 2016
CHANG Young-Tae (Group Leader, Chemistry)


NUS biophysicists have invented an artificial enzymatic nanowalker with record fuel efficiency by mimicking biological counterparts.
07 Jul 2016
WANG Zhisong (Group Leader, Physics)


NUS scientists have developed an optical method for measuring the instantaneous Brownian velocity of colloidal suspensions using upconversion nanothermometry.
05 Jul 2016
LIU Xiaogang (Group Leader, Chemistry)


NUS scientists have developed research which establishes the correctness of numerical methods used for important statistical applications.
30 Jun 2016
Ajay JASRA (Group Leader, Statistics and Applied Probability)


Organic chemistry
Resisting the urge to burn!
NUS researchers have developed new halodefluorination reaction with potential for new flame retardant materials.
27 Jun 2016
Rowan YOUNG (Group Leader, Chemistry)


NUS scientists have discovered new molecules which have a dual action to combat resistant malaria.
23 Jun 2016
Brian DYMOCK (Group Leader, Pharmacy)


Scientists in NUS discovered novel defect states at grain boundaries (GBs) in a two-dimensional (2D) semiconductor.
20 Jun 2016
Andrew WEE (Group Leader, Physics)


NUS scientists have identified the protein MOAP-1 as a potential treatment target for acute liver failure triggered by activation of a cell suicide program.
17 Jun 2016
Victor YU (Group Leader, Pharmacy)


Scientists in NUS discovered that Google Trends search patterns show that interest on key conservation topics is not declining over time and that search peaks are driven by online news.
13 Jun 2016
Roman CARRASCO (Group Leader, Biological Sciences)


Food scientists in NUS have identified a potent and highly selective inhibitor from traditional Chinese medicine, called dragon’s blood, to control high blood glucose.
09 Jun 2016
HUANG Dejian (Group Leader, Chemistry)


NUS scientists discovered a molecular mechanism which allows cellular processes to control the physiology and proteinopathy of TDP-43 whose aggregation is characteristic of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and many other ageing-related human diseases.
07 Jun 2016
SONG Jianxing (Group Leader, Biological Sciences)


NUS physicists have observed special photoresponse behaviour from a new two-dimensional (2D) semiconductor.
02 Jun 2016
SOW Chorng Haur (Group Leader, Physics)


NUS scientists have discovered Floquet topological semimetal phases in a simple dynamical model.
30 May 2016
GONG Jiangbin (Group Leader, Physics)


NUS physicists discovered a new way of transferring magnetic information across an insulator, paving the way for the development of devices that operate in the teraherz frequency range.
25 May 2016
ARIANDO (Group Leader, Physics)


NUS scientists have discovered a unique demonstration of how biomimetic interfaces can be used to probe and understand the influence of the microenvironment on the cellular process.
23 May 2016
Virgile VIASNOFF (Group Leader, Biological Sciences)


NUS scientists have developed a simple sampling method for soft fruit flesh using a conventional syringe needle for mapping the three-dimensional (3D) distribution of vitamin C.
19 May 2016
LEE Hian Kee (Group Leader, Chemistry)


Scientists in NUS discovered new small synthetic molecules with the aim of each molecule inhibiting two enzymes simultaneously, thus giving rise to potential anticancer properties.
16 May 2016
CHUI Wai Keung (Group Leader, Pharmacy)


NUS food scientists explore and expand the potential use of soybean residue (okara), a food processing waste, by yeast fermentation.
13 May 2016
LIU Shao-Quan (Group Leader, Chemistry)


NUS physicists have shown that giant photoluminescence (PL) enhancement is demonstrated by suspending the two-dimensional (2D) semiconductor WSe2 on sub-20 nanometre (nm) wide trenches in gold nanoarray substrates.
09 May 2016
Andrew WEE (Group Leader, Physics)


Scientists in NUS developed a new strategy to prepare acene dimers which have extremely high stability in ambient light and air conditions.
07 May 2016
CHI Chunyan (Group Leader, Chemistry)


Mechanobiology & Molecular cells
Mechanical barrier to cancer cell proliferation
Researchers in NUS discovered the differential effect of extracellular matrix (ECM) topographical cues on healthy and cancer cell proliferation.
05 May 2016
LOW Boon Chuan (Group Leader, Biological sciences)


NUS scientists have identified bacterial osmoporin OmpC as a functional component of the system that maintains outer membrane lipid asymmetry.
03 May 2016
CHNG Shu Sin (Group Leader, Chemistry)


NUS scientist wins the Young Researcher Award for ground-breaking work in molecular electronics.
29 Apr 2016
Christian NIJHUIS (Group Leader, Chemistry)


Bioimaging sciences
Diffraction before destruction
Scientists in NUS have demonstrated how x-ray lasers could help us image biological macromolecules in water.
26 Apr 2016
Duane LOH (Group Leader, Biological Sciences)


Scientists in NUS have uncovered a novel function of Nucleolar spindle-associated protein (NuSAP) in chromosome segregation.
22 Apr 2016
LIOU Yih-Cherng (Group Leader, Biological sciences)


NUS scientists have discovered for the first time that dronedarone inhibits human cardiac cytochrome P450 2J2 (CYP2J2).
18 Apr 2016
Eric CHAN (Group Leader, Pharmacy)


NUS biophysicists have developed a new generation of nanomotors, which potentially serve as ‘engines’ to power future nanotechnology at large.
14 Apr 2016
WANG Zhisong (Group Leader, Physics)


Mathematicians in NUS have developed a new theory and technique for database query optimisation.
11 Apr 2016
TAY Yong Chiang (Group Leader, Mathematics)


An in situ Transmission Electron Microscopy (TEM) study reveals that water molecules bound to nanoparticle surfaces serve as a barrier that stall their pairwise attachment.
07 Apr 2016
Utkur MIRSAIDOV (Group Leader, Biological Sciences)


Structural biology
New hope for HBV carriers
NUS scientists have discovered the mechanisms of mAb mediated HBsAg clean-up, a critical step towards development of therapeutic mAbs for Hepatitis B virus (HBV) carrier treatment.
04 Apr 2016
Adam YUAN (Group Leader, Biological Sciences)


NUS biologists discovered the mechanistic understanding of silk formation, the spinning process, and property-structure relationship as the key to mass-produce man-made spider silk.
29 Mar 2016
YANG Daiwen (Group Leader, Biological Sciences)


NUS food scientists have shown that fortifying bread with anthocyanin-rich extract slows down its digestion rate and adds health benefits.
28 Mar 2016
ZHOU Weibiao (Group Leader, Chemistry)


NUS scientists reported that international trade causes large net economic losses in tropical countries through the destruction of ecosystem services.
24 Mar 2016
Roman CARRASCO (Group Leader, Biological Sciences)


NUS food scientists develop the eucheuma-based packaged beverages with no added sugar and preservatives with a local company YGC Group.
21 Mar 2016
YANG Hongshun (Group Leader, Chemistry)


NUS scientists discover new organoruthenium anticancer complexes able to overcome multidrug resistance (MDR) by inducing alternative modes of cell death.
17 Mar 2016
ANG Wee Han (Group Leader, Chemistry)


Biodiversity
A new frog species
Researchers in NUS engage with citizens in India to describe the new species of frog as Microhyla laterite.
14 Mar 2016
Seshadri K S (Group Leader, Biological Sciences)


Scientists in NUS discovered visible surface plasmon modes in Bi2Te3 topological insulator nanoplates and obtained real space imaging of the plasmon modes for the first time.
11 Mar 2016
LOH Kian Ping (Group Leader, Chemistry)


NUS scientists invent new method and are planning to apply it to estimate undetected extinction in a wide range of animals and plants to assess impacts of deforestation and/or urbanisation on nature.
08 Mar 2016
Ryan CHISHOLM (Group Leader, Biological Sciences)


Researchers from NUS and the A*STAR designed a friendly inhalation treatment for a rare but serious condition.
04 Mar 2016
CHAN Sui Yung (Group Leader, Pharmacy)


NUS scientists have established the mechanisms for spin motion in molybdenum disulfide, an emerging two-dimensional (2D) material.
29 Feb 2016
Goki EDA (Group Leader, Physics)


NUS scientists are studying how to stop blood from clotting while not causing uncontrollable bleeding at similar doses.
25 Feb 2016
Kini R MANJUNATHA (Group Leader, Biological Sciences)


Scientists in NUS have developed a very low threshold, multi-photon pumped laser based on a solution of colloidal semiconductor nanoplatelets in a thin quartz cuvette.
23 Feb 2016
CHAN Yin Thai (Group Leader, Chemistry)


NUS scientists discovered that the dynamics of an “insoluble” protein and its interaction with membranes hold clues for the mechanism and progression of ALS.
15 Feb 2016
SONG Jianxing (Group Leader, Biological Sciences)


NUS researchers developed photomasks consisting of microlenses to make microneedles.
12 Feb 2016
KANG Li Feng (Group Leader, Pharmacy)


Computational mathematics
Wetting transition on patterned surfaces
NUS mathematicians investigate the liquid-vapour transition on patterned surfaces in shear flow using the minimum action method developed based on the large deviation theory.
10 Feb 2016
REN Weiqing (Group Leader, Mathematics)


NUS scientists discover that a plant-type Pin1, Pin1At, a peptidyl-prolyl isomerase, can regulate root growth in response to gravity by mediating a hormone pathway in plants.
05 Feb 2016
LIOU Yih-Cherng (Group Leader, Biological Sciences)


NUS scientists have discovered new molecules which release small amounts of H2S gas resulting in potent anti-cancer effects.
02 Feb 2016
Brian DYMOCK (Group Leader, Pharmacy)


NUS scientists have investigated how different transcription factors interact in embryonic and neuronal stem cells.
29 Jan 2016
Thorsten WOHLAND (Group Leader, Biological Sciences)


Organic chemistry
A new synthetic method
NUS chemists reported a new synthetic method of introducing an alkynyl group at β-position of cyclic carbonyl compounds with high enantioselectivity.
21 Jan 2016
Tamio HAYASH (Group Leader, Chemistry)


NUS pharmaceutical scientists showed remarkable improvement in oral absorption of HIV drugs.
18 Jan 2016
Gigi CHIU (Group Leader, Pharmacy)


NUS scientists studied the regulatory system, recruiting machinery and translocation apparatus to deliver-virulence proteins into host cells to cause infection.
13 Jan 2016
Jayaraman SIVARAMAN (Group Leader, Biological Sciences)


NUS scientist wins the 2015 L’Oréal FWIS National Fellowship in conservation of giant clams.
09 Jan 2016
NEO Mei Lin (Group Leader, Biological Sciences)


NUS professors measured phonon modes during hexagonal boron nitride growth using a surface sensitive technique.
05 Jan 2016
LOH Kian Ping (Group Leader, Chemistry)


Research News from Faculty of Science

NUS physicists have designed and successively micro-fabricated a miniature ion beam source prototype, paving the way to improve ion beam brightness by up to a million times.
22 Mar 2017
Jeroen Anton VAN KAN (Group Leader, Physics)


NUS biologists have developed small peptides which are able to target cancer cells for anti-cancer therapeutics.
17 Mar 2017
GE Ruowen (Group Leader, Biological Sciences)


NUS physicists have found a new type of black hole that can exist in anti-de Sitter space, whose event horizon is infinite in extent yet has a finite area.
13 Mar 2017
Edward TEO (Group Leader, Physics)


NUS biologists are assembling a comprehensive checklist of bee species and their distributions to assess pollinator declines.
08 Mar 2017
John ASCHER (Group Leader, Biological Sciences)


NUS chemists discover that oxygen gas is vital for the alcohol dehydrogenation process at low temperatures.
02 Mar 2017
CHUAH Gaik Khuan (Group Leader, Chemistry)


NUS ecologists used a survey-based method to study the economic impacts of trans-boundary haze.
23 Feb 2017
Ryan CHISHOLM (Group Leader, Biological Sciences)


NUS chemists have developed a method to make two-dimensional (2D) polymers with high energy storage performance for batteries.
20 Feb 2017
LOH Kian Ping (Group Leader, Chemistry)


NUS mathematicians have developed effective methods for modelling real-life problems with monotone density ratio conditions.
16 Feb 2017
YU Tao (Group Leader, Statistics and Applied Probability)


NUS biological scientists discover hidden targets on dengue virus during transmission into human hosts.
10 Feb 2017
Ganesh ANAND (Group Leader, Biological Sciences)


NUS chemists have developed new iron-catalysed reactions for producing molecules used in pharmaceutical drug production.
06 Feb 2017
GE Shaozhong (Group Leader, Chemistry)


NUS statisticians gain insights which allow for better prediction of physical phenomena.
01 Feb 2017
Alexandre THIERY (Group Leader, Statistics and Applied Probability)


Green chemistry
Cooperativity in catalysis
NUS chemists have discovered an operationally simple process to synthesise Z-enediyne, a potent class of anticancer warhead.
25 Jan 2017
ZHAO Yu (Group Leader, Chemistry)


NUS statisticians have developed a method to estimate unknown parameters efficiently for modelling complex situations.
19 Jan 2017
David NOTT (Group Leader, Statistics and Applied Probability)


NUS biological scientists have unravelled principles underlying pulsatile cell dynamics, a key step towards understanding biological networks.
16 Jan 2017
Wu Min (Group Leader, Biological Sciences)


NUS statisticians have developed adaptive functional time series models that improve the forecast accuracy of complex data such as term structure of interest rates, limit order book liquidity and electricity price curves.
11 Jan 2017
CHEN Ying (Group Leader, Statistics and Applied Probability)


NUS pharmaceutical scientists have developed new antimicrobial peptides that are effective against multidrug-resistant tuberculosis.
06 Jan 2017
Rachel EE (Group Leader, Pharmacy)


NUS scientists have discovered how FTO (or fat mass and obesity-associated protein), a protein strongly associated with obesity and diabetes, opens new treatment options for these metabolic diseases.
03 Jan 2017
Esther WOON (Group Leader, Pharmacy)


NUS chemists have developed photo-catalysts with enhanced catalytic properties for wastewater treatment.
22 Dec 2016
Sam LI (Group Leader, Chemistry)


NUS physicists have discovered fluorescent concentric triangles in an atomically thin layer of semiconductor for potential optoelectronic applications.
19 Dec 2016
SOW Chorng Haur (Group Leader, Physics)


NUS clinician scientists have demonstrated the value of a screening tool to detect diabetes distress among the local patient population.
13 Dec 2016
Joyce LEE (Group Leader, Pharmacy)


NUS physicists have developed a new form of super-resolution fluorescence microscopy for biomedical applications by using highly focused mega-electron volt (MeV) ion beams.
07 Dec 2016
Andrew BETTIOL (Group Leader, Physics)


NUS chemists have developed a synthesis approach to link semiconductor nanoparticles in a site-specific, stoichiometrically controlled manner analogous to molecular synthesis.
01 Dec 2016
CHAN Yin Thai (Group Leader, Chemistry)


NUS marine researchers are boosting local marine research and sustainability efforts to cope with emerging challenges brought about by climate change and urbanisation.
28 Nov 2016
Peter TODD and HUANG Danwei (Group Leaders, Biological Sciences)


NUS scientists in collaboration with Cambridge Display Technology Ltd (CDT) have developed solution-processed conducting polymer materials with ultrawide range of work functions for flexible electronics.
24 Nov 2016
Peter HO and CHUA Lay-Lay (Group Leaders, Physics and Chemistry)


Materials science
Tortuous path to nanocrystals
NUS researchers observed the crystallisation of gold particles in real-time in an aqueous solution in clear violation of classical nucleation theory.
21 Nov 2016
Utkur MIRSAIDOV and Duane LOH (Group Leaders, Physics and Biological Sciences)


NUS mathematicians have developed an unbiased and consistent estimator for counting motif (pattern) of gene regulatory relationships.
17 Nov 2016
ZHANG Louxin (Group Leader, Mathematics)


NUS mathematicians have developed an efficient and stable numerical method to solve fluid structure interaction problems involving large convections of fluid and near-contact of structures.
14 Nov 2016
LIU Jie (Group Leader, Mathematics)


NUS pharmaceutical scientists have developed techniques to modify lactose carrier particles in dry powder inhalers for efficient drug delivery to the lungs.
10 Nov 2016
Paul HENG (Group Leader, Pharmacy)


NUS biologist is part of the team that have discovered an important step in the development of ALS (amyotrophic lateral sclerosis), a neurodegenerative disease that is fatal.
07 Nov 2016
Kunchithapadam SWAMINATHAN (Group Leader, Biological Sciences)


NUS biologists have discovered a mechanism explaining why motor neurons are more vulnerable and degenerate first in a common neurodegenerative disease.
03 Nov 2016
Christoph WINKLER (Group Leader, Biological Sciences)


NUS scientists have published a report to revise the 30-year old polaron band model for doped organic semiconductors.
31 Oct 2016
Peter HO and CHUA Lay-Lay (Group Leaders, Physics and Chemistry)


NUS scientists have developed the first scaleable robust, open-sourced reconstruction algorithm targeted specifically for lens-less imaging with x-ray lasers.
27 Oct 2016
Duane LOH (Group Leader, Biological Sciences and Physics)


NUS mathematicians have provided a theoretical justification of trend-following trading strategies.
24 Oct 2016
DAI Min (Group Leader, Mathematics)


NUS scientists have developed on-chip molecular electronic plasmon sources without using optical elements for ultra-high speed electronics.
19 Oct 2016
Christian NIJHUIS (Group Leader, Chemistry)


NUS marine ecologists develop structurally complex tiles with relevant microhabitats and a large-scale deployment strategy for enhancing intertidal biodiversity on seawalls in Singapore.
14 Oct 2016
Peter TODD (Group Leader, Biological Sciences)


NUS biologists used a safe insect virus as gene therapy vectors to treat bladder cancer in mouse tumour models.
13 Oct 2016
WANG Shu (Group Leader, Biological Sciences)


NUS biologists have discovered that campotothecin (CPT), a highly selective DNA topoisomerase 1 (TOP1) inhibitor, targets stem cells in the root of the non-CPT-producing weed Arabidopsis thaliana.
10 Oct 2016
XU Jian (Group Leader, Biological Sciences)


NUS physicists have developed a high performance photodetector built on a hybrid bilayer of tungsten diselenide (WSe2) and perovskite.
06 Oct 2016
SOW Chorng Haur (Group Leader, Physics)


NUS food scientists discovered that human smell sensitivity changes with age, depending on the type of smells.
03 Oct 2016
HUANG Dejian (Group Leader, Chemistry)


NUS researchers establish association between dam construction and the increase in the proportion of non-native species in freshwater fish communities.
29 Sep 2016
Darren YEO (Group Leader, Biological Sciences)


NUS researchers have discovered that a protein, present in cells - talin - is able to sense and buffer cells against external forces.
26 Sep 2016
YAN Jie (Group Leader, Physics)


NUS food scientists have developed an edible coating which can preserve the quality of chilled fish fillets.
22 Sep 2016
YANG Hongshun (Group Leader, Chemistry)


NUS pharmacists discover that the quality of life of pre-dialysis patients may be affected more by a pill burden than complications associated with chronic kidney disease (CKD).
20 Sep 2016
Priscilla HOW (Group Leader, Pharmacy)


NUS scientists have discovered the mechanism of aggregation enhanced two-photon photoluminescence (2PPL) of metal nanoparticles by studying 2PPL properties of Au nanorod-nanosphere (NR-NS) heterodimers on the single particle level.
15 Sep 2016
XU Qing Hua (Group Leader, Chemistry)


NUS pharmacists have discovered signatures of diabetic retinopathy in blood samples which can identify those at a higher risk.
13 Sep 2016
Eric CHAN (Group Leader, Pharmacy)


NUS chemists have developed a new method of using phosphine catalysts to produce organic compounds with high stereoselectivity.
08 Sep 2016
LU Yixin (Group Leader, Chemistry)


Statistical methodology
Taking the high road
NUS statisticians have developed a “slope-assisted Hamiltonian Monte Carlo” sampling method to draw samples automatically from complex posterior distributions.
05 Sep 2016
Sanjay CHAUDHURI (Group Leader, Statistics and Applied Probability)


Electrochemistry
Greening our world
NUS chemists have developed a type of copper-based catalyst, which could efficiently reduce carbon dioxide, a greenhouse gas, into n-propanol.
01 Sep 2016
Jason YEO (Group Leader, Chemistry)


NUS mathematicians have formulated an equation for designing efficient memory allocation techniques for computer systems.
29 Sep 2016
TAY Yong Chiang (Group Leader, Mathematics)


NUS biologists have developed an effective method for protein extraction from green algae to detect environmental pollutants.
25 Aug 2016
LIN Qingsong (Group Leader, Biological Sciences)


Advanced materials
A new class of materials
NUS physicists and collaborators have developed ultra-thin films of a new class of materials: Weyl semi-metals.
22 Aug 2016
Adam SHAFFIQUE (Group Leader, Physics)


NUS scientists have found that most tropical butterflies tend to feed on a variety of flowers but some species are very selective in their diet.
19 Aug 2016
Edward WEBB (Group Leader, Biological Sciences)


NUS food scientists proved the potential of blue light-emitting diodes (LEDs) in killing deadly bacteria in orange juice.
15 Aug 2016
YUK Hyun-Gyun (Group Leader, Chemistry)


NUS scientists used flies to document rapid changes in the evolution of genome size in animals.
11 Aug 2016
Rudolf MEIER (Group Leader, Biological Sciences)


NUS scientists have developed multi-component nanocomposites which function as efficient visible-light photocatalysts with excellent magnetic recoverability.
08 Aug 2016
CHEN Wei (Group Leader, Chemistry and Physics)


Scientists in NUS conducted field experiments using paper models of butterflies to show how particular features of their wing patterns affected predation risk in the wild.
04 Aug 2016
Antónia MONTEIRO (Group Leader, Biological Sciences)


Advanced materials
A see-through metal
NUS scientists discover a way to enhance light transmission through an opaque metal surface by adding an atomically thin layer of semiconductor.
01 Aug 2016
Goki EDA (Group Leader, Chemistry and Physics)


NUS statisticians have developed a model which accounts for hidden factors and their effects for improved accuracy from economic data.
27 Jul 2016
LI Jialiang (Group Leader, Statistics and Applied Probability)


NUS scientists have synthesised the cDNA clone of the Brazilian variant of the hibiscus plant virus.
25 Jul 2016
WONG Sek Man (Group Leader, Biological Sciences)


NUS researchers develop a new theory which captures the dramatic fluctuations in species population abundances often observed in nature.
21 Jul 2016
Ryan CHISHOLM (Group Leader, Biological sciences)


NUS food scientists come up with the world’s first coffee fermented the old-fashioned way, with a food grade fungus Rhizopus oligosporus.
18 Jul 2016
LIU Shao Quan (Group Leader, Chemistry)


NUS biological scientists have identified the genes responsible for defending stem cells against viral infections.
14 Jul 2016
Jonathan LOH (Group Leader, Biological Sciences)


NUS chemists have developed a model for designing cell-permeable fluorescent probes with little background interference for bioimaging of living cells.
11 Jul 2016
CHANG Young-Tae (Group Leader, Chemistry)


NUS biophysicists have invented an artificial enzymatic nanowalker with record fuel efficiency by mimicking biological counterparts.
07 Jul 2016
WANG Zhisong (Group Leader, Physics)


NUS scientists have developed an optical method for measuring the instantaneous Brownian velocity of colloidal suspensions using upconversion nanothermometry.
05 Jul 2016
LIU Xiaogang (Group Leader, Chemistry)


NUS scientists have developed research which establishes the correctness of numerical methods used for important statistical applications.
30 Jun 2016
Ajay JASRA (Group Leader, Statistics and Applied Probability)


Organic chemistry
Resisting the urge to burn!
NUS researchers have developed new halodefluorination reaction with potential for new flame retardant materials.
27 Jun 2016
Rowan YOUNG (Group Leader, Chemistry)


NUS scientists have discovered new molecules which have a dual action to combat resistant malaria.
23 Jun 2016
Brian DYMOCK (Group Leader, Pharmacy)


Scientists in NUS discovered novel defect states at grain boundaries (GBs) in a two-dimensional (2D) semiconductor.
20 Jun 2016
Andrew WEE (Group Leader, Physics)


NUS scientists have identified the protein MOAP-1 as a potential treatment target for acute liver failure triggered by activation of a cell suicide program.
17 Jun 2016
Victor YU (Group Leader, Pharmacy)


Scientists in NUS discovered that Google Trends search patterns show that interest on key conservation topics is not declining over time and that search peaks are driven by online news.
13 Jun 2016
Roman CARRASCO (Group Leader, Biological Sciences)


Food scientists in NUS have identified a potent and highly selective inhibitor from traditional Chinese medicine, called dragon’s blood, to control high blood glucose.
09 Jun 2016
HUANG Dejian (Group Leader, Chemistry)


NUS scientists discovered a molecular mechanism which allows cellular processes to control the physiology and proteinopathy of TDP-43 whose aggregation is characteristic of amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and many other ageing-related human diseases.
07 Jun 2016
SONG Jianxing (Group Leader, Biological Sciences)


NUS physicists have observed special photoresponse behaviour from a new two-dimensional (2D) semiconductor.
02 Jun 2016
SOW Chorng Haur (Group Leader, Physics)


NUS scientists have discovered Floquet topological semimetal phases in a simple dynamical model.
30 May 2016
GONG Jiangbin (Group Leader, Physics)


NUS physicists discovered a new way of transferring magnetic information across an insulator, paving the way for the development of devices that operate in the teraherz frequency range.
25 May 2016
ARIANDO (Group Leader, Physics)


NUS scientists have discovered a unique demonstration of how biomimetic interfaces can be used to probe and understand the influence of the microenvironment on the cellular process.
23 May 2016
Virgile VIASNOFF (Group Leader, Biological Sciences)


NUS scientists have developed a simple sampling method for soft fruit flesh using a conventional syringe needle for mapping the three-dimensional (3D) distribution of vitamin C.
19 May 2016
LEE Hian Kee (Group Leader, Chemistry)


Scientists in NUS discovered new small synthetic molecules with the aim of each molecule inhibiting two enzymes simultaneously, thus giving rise to potential anticancer properties.
16 May 2016
CHUI Wai Keung (Group Leader, Pharmacy)


NUS food scientists explore and expand the potential use of soybean residue (okara), a food processing waste, by yeast fermentation.
13 May 2016
LIU Shao-Quan (Group Leader, Chemistry)


NUS physicists have shown that giant photoluminescence (PL) enhancement is demonstrated by suspending the two-dimensional (2D) semiconductor WSe2 on sub-20 nanometre (nm) wide trenches in gold nanoarray substrates.
09 May 2016
Andrew WEE (Group Leader, Physics)


Scientists in NUS developed a new strategy to prepare acene dimers which have extremely high stability in ambient light and air conditions.
07 May 2016
CHI Chunyan (Group Leader, Chemistry)


Mechanobiology & Molecular cells
Mechanical barrier to cancer cell proliferation
Researchers in NUS discovered the differential effect of extracellular matrix (ECM) topographical cues on healthy and cancer cell proliferation.
05 May 2016
LOW Boon Chuan (Group Leader, Biological sciences)


NUS scientists have identified bacterial osmoporin OmpC as a functional component of the system that maintains outer membrane lipid asymmetry.
03 May 2016
CHNG Shu Sin (Group Leader, Chemistry)


NUS scientist wins the Young Researcher Award for ground-breaking work in molecular electronics.
29 Apr 2016
Christian NIJHUIS (Group Leader, Chemistry)


Bioimaging sciences
Diffraction before destruction
Scientists in NUS have demonstrated how x-ray lasers could help us image biological macromolecules in water.
26 Apr 2016
Duane LOH (Group Leader, Biological Sciences)


Scientists in NUS have uncovered a novel function of Nucleolar spindle-associated protein (NuSAP) in chromosome segregation.
22 Apr 2016
LIOU Yih-Cherng (Group Leader, Biological sciences)


NUS scientists have discovered for the first time that dronedarone inhibits human cardiac cytochrome P450 2J2 (CYP2J2).
18 Apr 2016
Eric CHAN (Group Leader, Pharmacy)


NUS biophysicists have developed a new generation of nanomotors, which potentially serve as ‘engines’ to power future nanotechnology at large.
14 Apr 2016
WANG Zhisong (Group Leader, Physics)


Mathematicians in NUS have developed a new theory and technique for database query optimisation.
11 Apr 2016
TAY Yong Chiang (Group Leader, Mathematics)


An in situ Transmission Electron Microscopy (TEM) study reveals that water molecules bound to nanoparticle surfaces serve as a barrier that stall their pairwise attachment.
07 Apr 2016
Utkur MIRSAIDOV (Group Leader, Biological Sciences)


Structural biology
New hope for HBV carriers
NUS scientists have discovered the mechanisms of mAb mediated HBsAg clean-up, a critical step towards development of therapeutic mAbs for Hepatitis B virus (HBV) carrier treatment.
04 Apr 2016
Adam YUAN (Group Leader, Biological Sciences)


NUS biologists discovered the mechanistic understanding of silk formation, the spinning process, and property-structure relationship as the key to mass-produce man-made spider silk.
29 Mar 2016
YANG Daiwen (Group Leader, Biological Sciences)


NUS food scientists have shown that fortifying bread with anthocyanin-rich extract slows down its digestion rate and adds health benefits.
28 Mar 2016
ZHOU Weibiao (Group Leader, Chemistry)


NUS scientists reported that international trade causes large net economic losses in tropical countries through the destruction of ecosystem services.
24 Mar 2016
Roman CARRASCO (Group Leader, Biological Sciences)


NUS food scientists develop the eucheuma-based packaged beverages with no added sugar and preservatives with a local company YGC Group.
21 Mar 2016
YANG Hongshun (Group Leader, Chemistry)


NUS scientists discover new organoruthenium anticancer complexes able to overcome multidrug resistance (MDR) by inducing alternative modes of cell death.
17 Mar 2016
ANG Wee Han (Group Leader, Chemistry)


Biodiversity
A new frog species
Researchers in NUS engage with citizens in India to describe the new species of frog as Microhyla laterite.
14 Mar 2016
Seshadri K S (Group Leader, Biological Sciences)


Scientists in NUS discovered visible surface plasmon modes in Bi2Te3 topological insulator nanoplates and obtained real space imaging of the plasmon modes for the first time.
11 Mar 2016
LOH Kian Ping (Group Leader, Chemistry)


NUS scientists invent new method and are planning to apply it to estimate undetected extinction in a wide range of animals and plants to assess impacts of deforestation and/or urbanisation on nature.
08 Mar 2016
Ryan CHISHOLM (Group Leader, Biological Sciences)


Researchers from NUS and the A*STAR designed a friendly inhalation treatment for a rare but serious condition.
04 Mar 2016
CHAN Sui Yung (Group Leader, Pharmacy)


NUS scientists have established the mechanisms for spin motion in molybdenum disulfide, an emerging two-dimensional (2D) material.
29 Feb 2016
Goki EDA (Group Leader, Physics)


NUS scientists are studying how to stop blood from clotting while not causing uncontrollable bleeding at similar doses.
25 Feb 2016
Kini R MANJUNATHA (Group Leader, Biological Sciences)


Scientists in NUS have developed a very low threshold, multi-photon pumped laser based on a solution of colloidal semiconductor nanoplatelets in a thin quartz cuvette.
23 Feb 2016
CHAN Yin Thai (Group Leader, Chemistry)


NUS scientists discovered that the dynamics of an “insoluble” protein and its interaction with membranes hold clues for the mechanism and progression of ALS.
15 Feb 2016
SONG Jianxing (Group Leader, Biological Sciences)


NUS researchers developed photomasks consisting of microlenses to make microneedles.
12 Feb 2016
KANG Li Feng (Group Leader, Pharmacy)


Computational mathematics
Wetting transition on patterned surfaces
NUS mathematicians investigate the liquid-vapour transition on patterned surfaces in shear flow using the minimum action method developed based on the large deviation theory.
10 Feb 2016
REN Weiqing (Group Leader, Mathematics)


NUS scientists discover that a plant-type Pin1, Pin1At, a peptidyl-prolyl isomerase, can regulate root growth in response to gravity by mediating a hormone pathway in plants.
05 Feb 2016
LIOU Yih-Cherng (Group Leader, Biological Sciences)


NUS scientists have discovered new molecules which release small amounts of H2S gas resulting in potent anti-cancer effects.
02 Feb 2016
Brian DYMOCK (Group Leader, Pharmacy)


NUS scientists have investigated how different transcription factors interact in embryonic and neuronal stem cells.
29 Jan 2016
Thorsten WOHLAND (Group Leader, Biological Sciences)


Organic chemistry
A new synthetic method
NUS chemists reported a new synthetic method of introducing an alkynyl group at β-position of cyclic carbonyl compounds with high enantioselectivity.
21 Jan 2016
Tamio HAYASH (Group Leader, Chemistry)


NUS pharmaceutical scientists showed remarkable improvement in oral absorption of HIV drugs.
18 Jan 2016
Gigi CHIU (Group Leader, Pharmacy)


NUS scientists studied the regulatory system, recruiting machinery and translocation apparatus to deliver-virulence proteins into host cells to cause infection.
13 Jan 2016
Jayaraman SIVARAMAN (Group Leader, Biological Sciences)


NUS scientist wins the 2015 L’Oréal FWIS National Fellowship in conservation of giant clams.
09 Jan 2016
NEO Mei Lin (Group Leader, Biological Sciences)


NUS professors measured phonon modes during hexagonal boron nitride growth using a surface sensitive technique.
05 Jan 2016
LOH Kian Ping (Group Leader, Chemistry)